O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
501 K 15 4 19 0.230 0.677 View mutations
502 D 10 9 19 0.482 0.480 View mutations
503 D 9 10 19 0.513 0.454 View mutations
504 T 8 11 19 0.533 0.426 View mutations
505 A 8 11 19 0.601 0.426 View mutations
506 S 17 2 19 0.148 0.664 View mutations
507 H 18 1 19 0.082 0.744 View mutations
508 E 2 17 19 0.891 0.336 View mutations
509 P 15 4 19 0.180 0.588 View mutations
510 A 19 0 19 0.009 0.640 View mutations
511 L 17 2 19 0.224 0.512 View mutations
512 H 10 9 19 0.432 0.463 View mutations
513 R 11 8 19 0.431 0.476 View mutations
514 D 1 18 19 0.947 0.373 View mutations
515 D 0 19 19 0.989 0.424 View mutations
516 L 4 15 19 0.750 0.444 View mutations
517 E 9 10 19 0.573 0.434 View mutations
518 S 2 17 19 0.872 0.395 View mutations
519 L 1 18 19 0.944 0.474 View mutations
520 L 0 19 19 0.987 0.473 View mutations
521 S 15 4 19 0.188 0.446 View mutations
522 E 1 18 19 0.914 0.489 View mutations
523 H 0 19 19 0.975 0.536 View mutations
524 T 14 5 19 0.282 0.489 View mutations
525 F 10 9 19 0.524 0.498 View mutations