O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 S 19 0 19 0.002 0.603 View mutations
477 G 17 2 19 0.118 0.680 View mutations
478 D 19 0 19 0.006 0.759 View mutations
479 V 18 1 19 0.078 0.816 View mutations
480 T 17 2 19 0.089 0.800 View mutations
481 P 17 2 19 0.162 0.833 View mutations
482 A 18 1 19 0.063 0.814 View mutations
483 P 19 0 19 0.005 0.884 View mutations
484 V 19 0 19 0.013 0.865 View mutations
485 E 19 0 19 0.011 0.835 View mutations
486 G 13 6 19 0.287 0.576 View mutations
487 V 19 0 19 0.023 0.862 View mutations
488 L 19 0 19 0.000 0.898 View mutations
489 A 19 0 19 0.000 0.810 View mutations
490 P 19 0 19 0.000 0.920 View mutations
491 S 19 0 19 0.006 0.924 View mutations
492 P 19 0 19 0.014 0.930 View mutations
493 A 18 1 19 0.076 0.823 View mutations
494 R 19 0 19 0.000 0.953 View mutations
495 L 18 1 19 0.094 0.918 View mutations
496 A 19 0 19 0.000 0.914 View mutations
497 P 19 0 19 0.042 0.966 View mutations
498 G 16 3 19 0.233 0.708 View mutations
499 P 19 0 19 0.003 0.924 View mutations
500 A 19 0 19 0.000 0.820 View mutations