O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 7 11 18 0.546 0.427 View mutations
2 S 19 0 19 0.059 0.593 View mutations
3 T 15 4 19 0.349 0.548 View mutations
4 G 16 3 19 0.191 0.520 View mutations
5 S 19 0 19 0.003 0.661 View mutations
6 V 19 0 19 0.010 0.581 View mutations
7 S 19 0 19 0.013 0.675 View mutations
8 D 19 0 19 0.010 0.648 View mutations
9 P 19 0 19 0.001 0.708 View mutations
10 E 19 0 19 0.010 0.649 View mutations
11 E 19 0 19 0.026 0.640 View mutations
12 M 18 1 19 0.114 0.732 View mutations
13 E 18 1 19 0.096 0.648 View mutations
14 L 9 10 19 0.442 0.456 View mutations
15 R 19 0 19 0.005 0.679 View mutations
16 G 19 0 19 0.002 0.701 View mutations
17 L 19 0 19 0.039 0.778 View mutations
18 Q 19 0 19 0.019 0.725 View mutations
19 R 19 0 19 0.022 0.754 View mutations
20 E 19 0 19 0.002 0.828 View mutations
21 Y 16 3 19 0.157 0.722 View mutations
22 P 19 0 19 0.016 0.856 View mutations
23 V 19 0 19 0.017 0.888 View mutations
24 P 19 0 19 0.024 0.916 View mutations
25 A 16 3 19 0.204 0.803 View mutations