O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 D 3 16 19 0.712 0.234 View mutations
52 P 16 3 19 0.205 0.782 View mutations
53 D 12 7 19 0.397 0.610 View mutations
54 G 19 0 19 0.026 0.943 View mutations
55 E 19 0 19 0.002 0.913 View mutations
56 E 19 0 19 0.006 0.934 View mutations
57 E 19 0 19 0.063 0.882 View mutations
58 R 19 0 19 0.007 0.974 View mutations
59 C 19 0 19 0.007 0.971 View mutations
60 A 19 0 19 0.003 0.971 View mutations
61 L 19 0 19 0.029 0.951 View mutations
62 G 19 0 19 0.001 0.968 View mutations
63 T 19 0 19 0.001 0.944 View mutations
64 A 19 0 19 0.002 0.910 View mutations
65 G 19 0 19 0.000 0.956 View mutations
66 S 19 0 19 0.004 0.933 View mutations
67 A 19 0 19 0.000 0.925 View mutations
68 E 18 1 19 0.145 0.886 View mutations
69 G 19 0 19 0.001 0.849 View mutations
70 C 19 0 19 0.001 0.821 View mutations
71 K 19 0 19 0.004 0.839 View mutations
72 R 19 0 19 0.016 0.814 View mutations
73 K 18 1 19 0.193 0.817 View mutations
74 R 16 3 19 0.214 0.733 View mutations
75 P 19 0 19 0.043 0.878 View mutations