O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 19 0 19 0.029 0.896 View mutations
27 K 19 0 19 0.048 0.883 View mutations
28 R 19 0 19 0.009 0.923 View mutations
29 P 19 0 19 0.016 0.889 View mutations
30 P 18 1 19 0.062 0.904 View mutations
31 L 19 0 19 0.001 0.944 View mutations
32 R 19 0 19 0.003 0.919 View mutations
33 G 19 0 19 0.009 0.948 View mutations
34 V 19 0 19 0.002 0.923 View mutations
35 E 19 0 19 0.017 0.913 View mutations
36 R 19 0 19 0.002 0.884 View mutations
37 S 19 0 19 0.010 0.822 View mutations
38 Y 19 0 19 0.051 0.821 View mutations
39 A 18 1 19 0.102 0.847 View mutations
40 S 18 1 19 0.071 0.803 View mutations
41 P 19 0 19 0.080 0.838 View mutations
42 S 19 0 19 0.012 0.819 View mutations
43 D 18 1 19 0.065 0.777 View mutations
44 N 19 0 19 0.022 0.881 View mutations
45 S 12 7 19 0.358 0.574 View mutations
46 S 19 0 19 0.051 0.831 View mutations
47 A 19 0 19 0.007 0.840 View mutations
48 E 19 0 19 0.008 0.856 View mutations
49 E 19 0 19 0.037 0.847 View mutations
50 E 19 0 19 0.054 0.851 View mutations