O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 R 18 1 19 0.124 0.845 View mutations
77 V 19 0 19 0.004 0.902 View mutations
78 A 19 0 19 0.013 0.899 View mutations
79 G 19 0 19 0.013 0.935 View mutations
80 G 19 0 19 0.008 0.930 View mutations
81 G 19 0 19 0.001 0.928 View mutations
82 G 19 0 19 0.005 0.930 View mutations
83 A 19 0 19 0.001 0.973 View mutations
84 G 19 0 19 0.000 0.974 View mutations
85 G 19 0 19 0.001 0.981 View mutations
86 S 19 0 19 0.002 0.984 View mutations
87 A 19 0 19 0.000 0.992 View mutations
88 G 19 0 19 0.001 0.986 View mutations
89 G 19 0 19 0.001 1.000 View mutations
90 G 19 0 19 0.000 0.958 View mutations
91 G 19 0 19 0.000 0.975 View mutations
92 K 19 0 19 0.010 0.969 View mutations
93 K 19 0 19 0.040 0.950 View mutations
94 P 19 0 19 0.003 0.965 View mutations
95 L 18 1 19 0.106 0.884 View mutations
96 P 19 0 19 0.069 0.903 View mutations
97 A 19 0 19 0.030 0.899 View mutations
98 K 19 0 19 0.094 0.894 View mutations
99 G 17 2 19 0.119 0.789 View mutations
100 S 16 3 19 0.243 0.734 View mutations