O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 L 16 3 19 0.252 0.197 View mutations
152 A 10 9 19 0.462 0.481 View mutations
153 S 12 7 19 0.399 0.402 View mutations
154 S 12 7 19 0.258 0.399 View mutations
155 Y 3 16 19 0.645 0.777 View mutations
156 I 6 13 19 0.591 0.645 View mutations
157 A 19 0 19 0.080 0.226 View mutations
158 H 7 12 19 0.577 0.589 View mutations
159 L 5 14 19 0.598 0.709 View mutations
160 R 5 14 19 0.695 0.660 View mutations
161 Q 19 0 19 0.132 0.388 View mutations
162 L 11 8 19 0.503 0.437 View mutations
163 L 17 2 19 0.290 0.243 View mutations
164 Q 19 0 19 0.087 0.379 View mutations
165 E 19 0 19 0.136 0.353 View mutations
166 D 13 6 19 0.313 0.443 View mutations
167 R 19 0 19 0.037 0.437 View mutations
168 Y 19 0 19 0.007 0.458 View mutations
169 E 19 0 19 0.045 0.462 View mutations
170 N 19 0 19 0.001 0.428 View mutations
171 G 19 0 19 0.010 0.423 View mutations
172 Y 19 0 19 0.001 0.436 View mutations
173 V 19 0 19 0.002 0.354 View mutations
174 H 19 0 19 0.075 0.408 View mutations
175 P 19 0 19 0.030 0.308 View mutations