O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 10 9 19 0.497 0.479 View mutations
127 F 10 9 19 0.542 0.481 View mutations
128 S 4 15 19 0.736 0.736 View mutations
129 R 1 18 19 0.881 0.773 View mutations
130 L 2 17 19 0.728 0.822 View mutations
131 K 17 2 19 0.127 0.205 View mutations
132 T 4 15 19 0.730 0.670 View mutations
133 S 4 15 19 0.732 0.715 View mutations
134 L 2 17 19 0.745 0.812 View mutations
135 P 2 17 19 0.797 0.848 View mutations
136 W 18 1 19 0.316 0.177 View mutations
137 V 12 7 19 0.490 0.379 View mutations
138 P 3 16 19 0.725 0.803 View mutations
139 P 12 7 19 0.479 0.395 View mutations
140 D 13 6 19 0.381 0.326 View mutations
141 T 7 12 19 0.601 0.619 View mutations
142 K 19 0 19 0.071 0.102 View mutations
143 L 17 2 19 0.207 0.160 View mutations
144 S 19 0 19 0.070 0.000 View mutations
145 K 18 1 19 0.162 0.140 View mutations
146 L 18 1 19 0.122 0.084 View mutations
147 D 19 0 19 0.149 0.074 View mutations
148 T 15 4 19 0.275 0.258 View mutations
149 L 13 6 19 0.401 0.342 View mutations
150 R 13 6 19 0.388 0.355 View mutations