O60682 (O60682)

Overview
Predicted structure (AF):
AF-O60682-F1-model_v4
Uniprot entry:
O60682
Gene:
O60682
Protein length:
206 residues
Mutations found:
3913
Benign based on D2Deep prediction:
3461 out of 3913 mutations
Pathogenic based on D2Deep prediction:
452 out of 3913 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3913 mutations across 206 unique positions. There are 3461 benign and 452 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 A 18 1 19 0.081 0.752 View mutations
102 A 19 0 19 0.036 0.702 View mutations
103 E 14 5 19 0.264 0.505 View mutations
104 C 18 1 19 0.123 0.557 View mutations
105 K 18 1 19 0.076 0.533 View mutations
106 Q 19 0 19 0.048 0.466 View mutations
107 S 19 0 19 0.001 0.405 View mutations
108 Q 19 0 19 0.011 0.476 View mutations
109 R 19 0 19 0.027 0.462 View mutations
110 N 19 0 19 0.001 0.446 View mutations
111 A 19 0 19 0.010 0.354 View mutations
112 A 19 0 19 0.012 0.363 View mutations
113 N 18 1 19 0.137 0.379 View mutations
114 A 19 0 19 0.024 0.293 View mutations
115 R 19 0 19 0.008 0.358 View mutations
116 E 19 0 19 0.066 0.312 View mutations
117 R 19 0 19 0.059 0.297 View mutations
118 A 18 1 19 0.197 0.310 View mutations
119 R 19 0 19 0.087 0.233 View mutations
120 M 18 1 19 0.149 0.288 View mutations
121 R 10 9 19 0.494 0.487 View mutations
122 V 11 8 19 0.425 0.454 View mutations
123 L 16 3 19 0.297 0.304 View mutations
124 S 12 7 19 0.391 0.405 View mutations
125 K 5 14 19 0.651 0.602 View mutations