O75204 (TMEM127)

Overview
Predicted structure (AF):
AF-O75204-F1-model_v4
Uniprot entry:
O75204
Gene:
TMEM127
Protein length:
238 residues
Mutations found:
4521
Benign based on D2Deep prediction:
2714 out of 4521 mutations
Pathogenic based on D2Deep prediction:
1807 out of 4521 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4521 mutations across 238 unique positions. There are 2714 benign and 1807 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 17 1 18 0.104 0.474 View mutations
2 Y 11 8 19 0.468 0.483 View mutations
3 A 6 13 19 0.662 0.363 View mutations
4 P 16 3 19 0.195 0.752 View mutations
5 G 19 0 19 0.013 0.858 View mutations
6 G 19 0 19 0.022 0.865 View mutations
7 A 17 2 19 0.072 0.895 View mutations
8 G 18 1 19 0.032 0.941 View mutations
9 L 19 0 19 0.024 0.888 View mutations
10 P 18 1 19 0.098 0.890 View mutations
11 G 19 0 19 0.008 0.861 View mutations
12 G 14 5 19 0.265 0.649 View mutations
13 R 16 3 19 0.235 0.737 View mutations
14 R 10 9 19 0.460 0.501 View mutations
15 R 19 0 19 0.057 0.880 View mutations
16 R 18 1 19 0.054 0.853 View mutations
17 S 14 5 19 0.248 0.705 View mutations
18 P 19 0 19 0.056 0.961 View mutations
19 G 15 4 19 0.197 0.766 View mutations
20 G 19 0 19 0.077 0.817 View mutations
21 S 12 7 19 0.364 0.592 View mutations
22 A 14 5 19 0.240 0.673 View mutations
23 L 7 12 19 0.593 0.412 View mutations
24 P 2 17 19 0.886 0.347 View mutations
25 K 8 11 19 0.558 0.433 View mutations