O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 L 6 13 19 0.714 0.516 View mutations
402 G 19 0 19 0.000 0.678 View mutations
403 E 19 0 19 0.000 0.776 View mutations
404 N 14 5 19 0.280 0.607 View mutations
405 L 18 1 19 0.058 0.507 View mutations
406 K 19 0 19 0.008 0.774 View mutations
407 I 19 0 19 0.000 0.827 View mutations
408 K 14 5 19 0.276 0.667 View mutations
409 L 19 0 19 0.001 0.698 View mutations
410 A 19 0 19 0.001 0.800 View mutations
411 Q 18 1 19 0.050 0.814 View mutations
412 A 13 6 19 0.327 0.592 View mutations
413 K 14 5 19 0.324 0.614 View mutations
414 L 16 3 19 0.161 0.611 View mutations