O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 L 19 0 19 0.032 0.302 View mutations
377 A 15 4 19 0.220 0.404 View mutations
378 A 13 6 19 0.283 0.493 View mutations
379 C 19 0 19 0.011 0.613 View mutations
380 I 17 2 19 0.104 0.573 View mutations
381 K 19 0 19 0.049 0.773 View mutations
382 G 16 3 19 0.223 0.701 View mutations
383 L 19 0 19 0.019 0.902 View mutations
384 P 19 0 19 0.003 0.911 View mutations
385 N 18 1 19 0.037 0.847 View mutations
386 V 19 0 19 0.008 0.856 View mutations
387 Q 19 0 19 0.007 0.937 View mutations
388 R 19 0 19 0.015 0.800 View mutations
389 S 19 0 19 0.011 0.783 View mutations
390 D 19 0 19 0.002 0.717 View mutations
391 Y 19 0 19 0.043 0.498 View mutations
392 L 19 0 19 0.001 0.405 View mutations
393 N 16 3 19 0.210 0.553 View mutations
394 T 19 0 19 0.026 0.376 View mutations
395 F 19 0 19 0.000 0.585 View mutations
396 E 19 0 19 0.015 0.551 View mutations
397 F 10 9 19 0.510 0.493 View mutations
398 M 12 7 19 0.342 0.433 View mutations
399 D 19 0 19 0.000 0.706 View mutations
400 K 19 0 19 0.040 0.613 View mutations