O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 E 19 0 19 0.002 0.716 View mutations
352 L 9 10 19 0.512 0.505 View mutations
353 A 19 0 19 0.033 0.756 View mutations
354 F 19 0 19 0.007 0.852 View mutations
355 F 16 3 19 0.260 0.499 View mutations
356 A 19 0 19 0.000 0.487 View mutations
357 N 19 0 19 0.001 0.775 View mutations
358 A 15 4 19 0.131 0.688 View mutations
359 L 2 17 19 0.876 0.640 View mutations
360 E 19 0 19 0.000 0.375 View mutations
361 E 19 0 19 0.009 0.771 View mutations
362 V 4 15 19 0.653 0.384 View mutations
363 S 9 10 19 0.534 0.504 View mutations
364 I 2 17 19 0.849 0.521 View mutations
365 E 14 5 19 0.259 0.597 View mutations
366 T 10 9 19 0.434 0.428 View mutations
367 I 12 7 19 0.400 0.435 View mutations
368 E 1 18 19 0.931 0.508 View mutations
369 A 18 1 19 0.044 0.597 View mutations
370 G 19 0 19 0.003 0.339 View mutations
371 F 19 0 19 0.000 0.597 View mutations
372 M 17 2 19 0.121 0.342 View mutations
373 T 0 19 19 1.000 0.738 View mutations
374 K 11 8 19 0.397 0.484 View mutations
375 D 0 19 19 0.988 0.649 View mutations