O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.647 View mutations
2 S 19 0 19 0.001 0.797 View mutations
3 K 19 0 19 0.010 0.713 View mutations
4 K 19 0 19 0.003 0.583 View mutations
5 I 19 0 19 0.000 0.760 View mutations
6 S 19 0 19 0.009 0.596 View mutations
7 G 19 0 19 0.003 0.765 View mutations
8 G 19 0 19 0.018 0.640 View mutations
9 S 18 1 19 0.136 0.467 View mutations
10 V 10 9 19 0.436 0.428 View mutations
11 V 12 7 19 0.338 0.495 View mutations
12 E 6 13 19 0.694 0.509 View mutations
13 M 4 15 19 0.752 0.506 View mutations
14 Q 12 7 19 0.317 0.490 View mutations
15 G 18 1 19 0.099 0.326 View mutations
16 D 19 0 19 0.012 0.274 View mutations
17 E 1 18 19 0.954 0.681 View mutations
18 M 1 18 19 0.955 0.592 View mutations
19 T 2 17 19 0.889 0.591 View mutations
20 R 18 1 19 0.047 0.443 View mutations
21 I 2 17 19 0.886 0.412 View mutations
22 I 18 1 19 0.065 0.447 View mutations
23 W 1 18 19 0.901 0.518 View mutations
24 E 18 1 19 0.036 0.612 View mutations
25 L 19 0 19 0.007 0.731 View mutations