P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.565 View mutations
2 T 16 3 19 0.109 0.631 View mutations
3 E 0 19 19 0.981 0.259 View mutations
4 Y 8 11 19 0.523 0.432 View mutations
5 K 8 11 19 0.614 0.435 View mutations
6 L 19 0 19 0.038 0.388 View mutations
7 V 17 2 19 0.168 0.416 View mutations
8 V 19 0 19 0.056 0.431 View mutations
9 V 5 14 19 0.783 0.448 View mutations
10 G 0 19 19 0.992 0.601 View mutations
11 A 14 5 19 0.326 0.469 View mutations
12 G 0 19 19 1.000 0.576 View mutations
13 G 1 18 19 0.965 0.578 View mutations
14 V 0 19 19 1.000 0.652 View mutations
15 G 19 0 19 0.083 0.368 View mutations
16 K 19 0 19 0.000 0.428 View mutations
17 S 1 18 19 0.945 0.484 View mutations
18 A 5 14 19 0.723 0.453 View mutations
19 L 5 14 19 0.757 0.442 View mutations
20 T 17 2 19 0.140 0.477 View mutations
21 I 0 19 19 0.994 0.365 View mutations
22 Q 12 7 19 0.313 0.467 View mutations
23 L 4 15 19 0.757 0.353 View mutations
24 I 3 16 19 0.802 0.361 View mutations
25 Q 0 19 19 0.951 0.364 View mutations