P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 D 18 1 19 0.038 0.787 View mutations
177 G 19 0 19 0.019 0.815 View mutations
178 T 19 0 19 0.001 0.833 View mutations
179 Q 19 0 19 0.004 0.858 View mutations
180 G 18 1 19 0.058 0.839 View mutations
181 C 19 0 19 0.000 1.000 View mutations
182 M 19 0 19 0.000 0.973 View mutations
183 G 19 0 19 0.001 0.935 View mutations
184 L 19 0 19 0.001 0.964 View mutations
185 P 19 0 19 0.001 0.956 View mutations
186 C 19 0 19 0.157 0.745 View mutations
187 V 19 0 19 0.001 0.811 View mutations
188 V 19 0 19 0.001 0.775 View mutations
189 M 19 0 19 0.063 0.703 View mutations