P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 C 1 18 19 0.947 0.431 View mutations
52 L 3 16 19 0.815 0.422 View mutations
53 L 0 19 19 1.000 0.659 View mutations
54 D 1 18 19 0.943 0.582 View mutations
55 I 19 0 19 0.006 0.279 View mutations
56 L 3 16 19 0.848 0.726 View mutations
57 D 0 19 19 1.000 0.846 View mutations
58 T 7 12 19 0.633 0.632 View mutations
59 A 1 18 19 0.871 0.858 View mutations
60 G 0 19 19 0.983 0.950 View mutations
61 Q 0 19 19 1.000 0.727 View mutations
62 E 0 19 19 1.000 0.741 View mutations
63 E 12 7 19 0.450 0.454 View mutations
64 Y 6 13 19 0.717 0.520 View mutations
65 S 4 15 19 0.770 0.527 View mutations
66 A 2 17 19 0.905 0.641 View mutations
67 M 0 19 19 0.977 0.593 View mutations
68 R 0 19 19 0.999 0.592 View mutations
69 D 16 3 19 0.222 0.427 View mutations
70 Q 9 10 19 0.560 0.508 View mutations
71 Y 0 19 19 0.989 0.641 View mutations
72 M 4 15 19 0.809 0.566 View mutations
73 R 0 19 19 0.984 0.633 View mutations
74 T 2 17 19 0.855 0.549 View mutations
75 G 0 19 19 0.923 0.678 View mutations