P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 N 16 3 19 0.191 0.526 View mutations
27 H 19 0 19 0.004 0.552 View mutations
28 F 13 6 19 0.341 0.428 View mutations
29 V 3 16 19 0.833 0.467 View mutations
30 D 10 9 19 0.555 0.427 View mutations
31 E 18 1 19 0.065 0.485 View mutations
32 Y 1 18 19 0.912 0.589 View mutations
33 D 0 19 19 1.000 0.612 View mutations
34 P 0 19 19 0.957 0.714 View mutations
35 T 0 19 19 1.000 0.723 View mutations
36 I 5 14 19 0.655 0.575 View mutations
37 E 7 12 19 0.579 0.523 View mutations
38 D 0 19 19 0.974 0.625 View mutations
39 S 0 19 19 1.000 0.581 View mutations
40 Y 1 18 19 0.935 0.514 View mutations
41 R 2 17 19 0.877 0.484 View mutations
42 K 7 12 19 0.618 0.518 View mutations
43 Q 19 0 19 0.000 0.422 View mutations
44 V 8 11 19 0.541 0.502 View mutations
45 V 2 17 19 0.795 0.424 View mutations
46 I 11 8 19 0.446 0.495 View mutations
47 D 9 10 19 0.549 0.500 View mutations
48 G 17 2 19 0.211 0.411 View mutations
49 E 10 9 19 0.483 0.444 View mutations
50 T 9 10 19 0.556 0.439 View mutations