P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 D 19 0 19 0.033 0.533 View mutations
127 T 19 0 19 0.057 0.633 View mutations
128 K 19 0 19 0.030 0.655 View mutations
129 Q 19 0 19 0.001 0.577 View mutations
130 A 5 14 19 0.662 0.440 View mutations
131 H 18 1 19 0.104 0.589 View mutations
132 E 19 0 19 0.035 0.551 View mutations
133 L 18 1 19 0.088 0.533 View mutations
134 A 16 3 19 0.153 0.422 View mutations
135 K 19 0 19 0.004 0.628 View mutations
136 S 19 0 19 0.019 0.695 View mutations
137 Y 13 6 19 0.317 0.545 View mutations
138 G 17 2 19 0.114 0.468 View mutations
139 I 14 5 19 0.282 0.475 View mutations
140 P 14 5 19 0.310 0.462 View mutations
141 F 17 2 19 0.125 0.517 View mutations
142 I 19 0 19 0.001 0.434 View mutations
143 E 19 0 19 0.000 0.308 View mutations
144 T 10 9 19 0.446 0.499 View mutations
145 S 19 0 19 0.061 0.299 View mutations
146 A 10 9 19 0.442 0.490 View mutations
147 K 8 11 19 0.596 0.436 View mutations
148 T 19 0 19 0.003 0.617 View mutations
149 R 19 0 19 0.006 0.504 View mutations
150 Q 19 0 19 0.000 0.523 View mutations