P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.035 0.466 View mutations
152 V 0 19 19 0.999 0.536 View mutations
153 E 19 0 19 0.056 0.466 View mutations
154 D 19 0 19 0.003 0.490 View mutations
155 A 1 18 19 0.916 0.410 View mutations
156 F 19 0 19 0.001 0.406 View mutations
157 Y 19 0 19 0.003 0.495 View mutations
158 T 18 1 19 0.046 0.528 View mutations
159 L 14 5 19 0.291 0.476 View mutations
160 V 19 0 19 0.019 0.448 View mutations
161 R 19 0 19 0.013 0.374 View mutations
162 E 12 7 19 0.377 0.502 View mutations
163 I 9 10 19 0.547 0.430 View mutations
164 R 17 2 19 0.125 0.530 View mutations
165 Q 19 0 19 0.001 0.719 View mutations
166 Y 19 0 19 0.014 0.818 View mutations
167 R 19 0 19 0.000 0.712 View mutations
168 M 19 0 19 0.003 0.776 View mutations
169 K 19 0 19 0.002 0.781 View mutations
170 K 19 0 19 0.000 0.776 View mutations
171 L 18 1 19 0.042 0.762 View mutations
172 N 19 0 19 0.001 0.810 View mutations
173 S 19 0 19 0.004 0.797 View mutations
174 S 19 0 19 0.001 0.844 View mutations
175 D 19 0 19 0.000 0.810 View mutations