P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 E 19 0 19 0.000 0.841 View mutations
177 S 19 0 19 0.006 0.860 View mutations
178 G 19 0 19 0.000 0.860 View mutations
179 P 19 0 19 0.000 0.902 View mutations
180 G 19 0 19 0.014 0.916 View mutations
181 C 19 0 19 0.000 0.975 View mutations
182 M 19 0 19 0.000 0.973 View mutations
183 S 19 0 19 0.001 0.951 View mutations
184 C 19 0 19 0.004 1.000 View mutations
185 K 19 0 19 0.000 0.928 View mutations
186 C 19 0 19 0.000 0.827 View mutations
187 V 19 0 19 0.001 0.813 View mutations
188 L 19 0 19 0.000 0.820 View mutations
189 S 19 0 19 0.015 0.795 View mutations