P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.058 0.499 View mutations
152 V 0 19 19 0.999 0.515 View mutations
153 E 13 6 19 0.363 0.459 View mutations
154 D 19 0 19 0.003 0.524 View mutations
155 A 3 16 19 0.882 0.398 View mutations
156 F 19 0 19 0.002 0.449 View mutations
157 Y 19 0 19 0.005 0.536 View mutations
158 T 19 0 19 0.030 0.580 View mutations
159 L 15 4 19 0.269 0.496 View mutations
160 V 19 0 19 0.021 0.360 View mutations
161 R 19 0 19 0.008 0.440 View mutations
162 E 13 6 19 0.346 0.543 View mutations
163 I 5 14 19 0.684 0.442 View mutations
164 R 13 6 19 0.304 0.517 View mutations
165 Q 19 0 19 0.002 0.787 View mutations
166 H 19 0 19 0.012 0.848 View mutations
167 K 19 0 19 0.001 0.807 View mutations
168 L 19 0 19 0.001 0.875 View mutations
169 R 19 0 19 0.003 0.868 View mutations
170 K 19 0 19 0.001 0.844 View mutations
171 L 19 0 19 0.012 0.855 View mutations
172 N 19 0 19 0.002 0.888 View mutations
173 P 19 0 19 0.002 0.859 View mutations
174 P 19 0 19 0.001 0.857 View mutations
175 D 19 0 19 0.000 0.850 View mutations