P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 E 19 0 19 0.016 0.575 View mutations
127 S 13 6 19 0.330 0.530 View mutations
128 R 17 2 19 0.112 0.643 View mutations
129 Q 19 0 19 0.000 0.609 View mutations
130 A 2 17 19 0.823 0.421 View mutations
131 Q 18 1 19 0.115 0.617 View mutations
132 D 17 2 19 0.152 0.562 View mutations
133 L 16 3 19 0.207 0.549 View mutations
134 A 10 9 19 0.474 0.434 View mutations
135 R 19 0 19 0.014 0.648 View mutations
136 S 18 1 19 0.055 0.693 View mutations
137 Y 12 7 19 0.359 0.528 View mutations
138 G 19 0 19 0.023 0.516 View mutations
139 I 14 5 19 0.312 0.496 View mutations
140 P 15 4 19 0.289 0.485 View mutations
141 Y 18 1 19 0.100 0.556 View mutations
142 I 19 0 19 0.008 0.465 View mutations
143 E 19 0 19 0.000 0.337 View mutations
144 T 9 10 19 0.533 0.430 View mutations
145 S 19 0 19 0.024 0.329 View mutations
146 A 11 8 19 0.441 0.474 View mutations
147 K 8 11 19 0.608 0.436 View mutations
148 T 19 0 19 0.004 0.635 View mutations
149 R 19 0 19 0.053 0.539 View mutations
150 Q 19 0 19 0.000 0.557 View mutations