P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.001 0.595 View mutations
2 T 19 0 19 0.051 0.741 View mutations
3 E 0 19 19 0.991 0.217 View mutations
4 Y 7 12 19 0.624 0.416 View mutations
5 K 9 10 19 0.507 0.436 View mutations
6 L 19 0 19 0.053 0.430 View mutations
7 V 16 3 19 0.200 0.444 View mutations
8 V 17 2 19 0.127 0.456 View mutations
9 V 4 15 19 0.812 0.439 View mutations
10 G 0 19 19 0.999 0.568 View mutations
11 A 14 5 19 0.268 0.486 View mutations
12 G 0 19 19 1.000 0.555 View mutations
13 G 0 19 19 0.993 0.571 View mutations
14 V 0 19 19 1.000 0.633 View mutations
15 G 15 4 19 0.268 0.436 View mutations
16 K 19 0 19 0.000 0.461 View mutations
17 S 2 17 19 0.912 0.448 View mutations
18 A 5 14 19 0.732 0.443 View mutations
19 L 1 18 19 0.890 0.424 View mutations
20 T 17 2 19 0.139 0.518 View mutations
21 I 0 19 19 0.998 0.333 View mutations
22 Q 14 5 19 0.297 0.504 View mutations
23 L 1 18 19 0.918 0.271 View mutations
24 I 3 16 19 0.828 0.340 View mutations
25 Q 0 19 19 0.953 0.339 View mutations