P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 K 18 1 19 0.078 0.882 View mutations
177 K 19 0 19 0.001 0.912 View mutations
178 K 19 0 19 0.000 0.922 View mutations
179 K 19 0 19 0.003 0.947 View mutations
180 K 19 0 19 0.025 0.971 View mutations
181 S 19 0 19 0.001 1.000 View mutations
182 K 19 0 19 0.002 0.993 View mutations
183 T 19 0 19 0.013 0.979 View mutations
184 K 19 0 19 0.005 0.952 View mutations
185 C 19 0 19 0.000 0.719 View mutations
186 V 19 0 19 0.004 0.817 View mutations
187 I 18 1 19 0.033 0.721 View mutations
188 M 19 0 19 0.003 0.668 View mutations