P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 G 19 0 19 0.030 0.573 View mutations
152 V 0 19 19 0.982 0.454 View mutations
153 D 19 0 19 0.024 0.533 View mutations
154 D 19 0 19 0.000 0.571 View mutations
155 A 2 17 19 0.865 0.361 View mutations
156 F 19 0 19 0.004 0.473 View mutations
157 Y 19 0 19 0.000 0.577 View mutations
158 T 19 0 19 0.029 0.613 View mutations
159 L 15 4 19 0.219 0.382 View mutations
160 V 19 0 19 0.001 0.417 View mutations
161 R 19 0 19 0.025 0.462 View mutations
162 E 13 6 19 0.371 0.567 View mutations
163 I 10 9 19 0.482 0.433 View mutations
164 R 19 0 19 0.055 0.688 View mutations
165 K 19 0 19 0.002 0.845 View mutations
166 H 19 0 19 0.001 0.935 View mutations
167 K 19 0 19 0.001 0.856 View mutations
168 E 19 0 19 0.007 0.906 View mutations
169 K 19 0 19 0.004 0.932 View mutations
170 M 19 0 19 0.007 0.975 View mutations
171 S 18 1 19 0.028 0.872 View mutations
172 K 19 0 19 0.000 0.936 View mutations
173 D 19 0 19 0.040 0.948 View mutations
174 G 19 0 19 0.003 0.963 View mutations
175 K 19 0 19 0.003 0.911 View mutations