P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 D 19 0 19 0.022 0.622 View mutations
127 T 19 0 19 0.010 0.695 View mutations
128 K 16 3 19 0.135 0.659 View mutations
129 Q 19 0 19 0.005 0.681 View mutations
130 A 7 12 19 0.647 0.425 View mutations
131 Q 15 4 19 0.262 0.600 View mutations
132 D 17 2 19 0.094 0.599 View mutations
133 L 18 1 19 0.071 0.636 View mutations
134 A 17 2 19 0.137 0.480 View mutations
135 R 19 0 19 0.020 0.705 View mutations
136 S 18 1 19 0.055 0.744 View mutations
137 Y 15 4 19 0.256 0.653 View mutations
138 G 19 0 19 0.019 0.552 View mutations
139 I 15 4 19 0.199 0.548 View mutations
140 P 15 4 19 0.274 0.502 View mutations
141 F 19 0 19 0.033 0.611 View mutations
142 I 19 0 19 0.001 0.514 View mutations
143 E 19 0 19 0.000 0.364 View mutations
144 T 12 7 19 0.355 0.419 View mutations
145 S 19 0 19 0.004 0.346 View mutations
146 A 11 8 19 0.424 0.471 View mutations
147 K 8 11 19 0.562 0.434 View mutations
148 T 19 0 19 0.023 0.720 View mutations
149 R 19 0 19 0.016 0.622 View mutations
150 Q 19 0 19 0.000 0.635 View mutations