P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 D 19 0 19 0.001 0.925 View mutations
252 G 19 0 19 0.006 0.912 View mutations
253 T 19 0 19 0.013 0.931 View mutations
254 P 19 0 19 0.016 0.869 View mutations
255 R 19 0 19 0.007 0.917 View mutations
256 G 19 0 19 0.015 0.903 View mutations
257 S 19 0 19 0.017 0.890 View mutations
258 P 19 0 19 0.018 0.922 View mutations
259 S 19 0 19 0.022 0.957 View mutations
260 P 19 0 19 0.067 0.884 View mutations
261 A 16 3 19 0.154 0.756 View mutations
262 S 18 1 19 0.110 0.845 View mutations
263 V 19 0 19 0.027 0.845 View mutations
264 S 19 0 19 0.047 0.898 View mutations
265 S 19 0 19 0.008 0.882 View mutations
266 G 19 0 19 0.002 0.853 View mutations
267 R 18 1 19 0.070 0.817 View mutations
268 K 19 0 19 0.007 0.865 View mutations
269 S 14 5 19 0.278 0.668 View mutations
270 P 11 8 19 0.413 0.554 View mutations
271 H 19 0 19 0.020 0.840 View mutations
272 S 18 1 19 0.082 0.798 View mutations
273 K 17 2 19 0.114 0.701 View mutations
274 S 14 5 19 0.276 0.639 View mutations
275 P 19 0 19 0.052 0.743 View mutations