P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 A 19 0 19 0.007 0.801 View mutations
277 E 19 0 19 0.013 0.828 View mutations
278 Q 19 0 19 0.001 0.754 View mutations
279 R 14 5 19 0.345 0.614 View mutations
280 E 16 3 19 0.270 0.634 View mutations
281 R 9 10 19 0.523 0.458 View mutations
282 K 19 0 19 0.004 0.767 View mutations
283 S 14 5 19 0.255 0.599 View mutations
284 L 16 3 19 0.189 0.696 View mutations
285 A 19 0 19 0.073 0.764 View mutations
286 D 19 0 19 0.003 0.701 View mutations
287 D 16 3 19 0.149 0.605 View mutations
288 K 6 13 19 0.610 0.378 View mutations
289 K 17 2 19 0.172 0.687 View mutations
290 K 16 3 19 0.174 0.614 View mutations
291 V 15 4 19 0.309 0.590 View mutations
292 K 3 16 19 0.838 0.339 View mutations
293 N 19 0 19 0.018 0.671 View mutations
294 L 17 2 19 0.105 0.569 View mutations
295 G 19 0 19 0.045 0.550 View mutations
296 Y 19 0 19 0.011 0.513 View mutations
297 R 1 18 19 0.963 0.507 View mutations
298 D 0 19 19 0.998 0.575 View mutations
299 S 0 19 19 0.998 0.531 View mutations
300 G 2 17 19 0.867 0.511 View mutations