P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 Y 8 11 19 0.550 0.510 View mutations
302 Y 17 2 19 0.096 0.410 View mutations
303 W 0 19 19 0.980 0.559 View mutations
304 E 0 19 19 0.999 0.614 View mutations
305 V 19 0 19 0.019 0.482 View mutations
306 P 18 1 19 0.061 0.514 View mutations
307 P 18 1 19 0.105 0.503 View mutations
308 S 19 0 19 0.001 0.479 View mutations
309 E 15 4 19 0.226 0.497 View mutations
310 V 3 16 19 0.817 0.446 View mutations
311 Q 18 1 19 0.056 0.579 View mutations
312 L 19 0 19 0.002 0.594 View mutations
313 L 19 0 19 0.007 0.562 View mutations
314 K 14 5 19 0.237 0.416 View mutations
315 R 5 14 19 0.761 0.517 View mutations
316 I 5 14 19 0.710 0.544 View mutations
317 G 0 19 19 0.998 0.644 View mutations
318 T 15 4 19 0.233 0.425 View mutations
319 G 0 19 19 1.000 0.726 View mutations
320 S 1 18 19 0.921 0.691 View mutations
321 F 0 19 19 0.970 0.733 View mutations
322 G 0 19 19 1.000 0.739 View mutations
323 T 3 16 19 0.858 0.670 View mutations
324 V 0 19 19 1.000 0.697 View mutations
325 F 1 18 19 0.955 0.581 View mutations