P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
576 K 8 11 19 0.582 0.511 View mutations
577 I 16 3 19 0.250 0.380 View mutations
578 E 19 0 19 0.011 0.402 View mutations
579 R 10 9 19 0.440 0.493 View mutations
580 S 5 14 19 0.680 0.573 View mutations
581 A 19 0 19 0.016 0.351 View mutations
582 S 1 18 19 0.947 0.639 View mutations
583 E 19 0 19 0.003 0.285 View mutations
584 P 9 10 19 0.474 0.510 View mutations
585 S 15 4 19 0.154 0.462 View mutations
586 L 11 8 19 0.443 0.485 View mutations
587 H 8 11 19 0.553 0.500 View mutations
588 R 1 18 19 0.932 0.513 View mutations
589 T 6 13 19 0.659 0.429 View mutations
590 Q 11 8 19 0.446 0.459 View mutations
591 A 12 7 19 0.381 0.471 View mutations
592 D 13 6 19 0.281 0.461 View mutations
593 E 19 0 19 0.007 0.469 View mutations
594 L 18 1 19 0.053 0.508 View mutations
595 P 8 11 19 0.538 0.431 View mutations
596 A 13 6 19 0.381 0.510 View mutations
597 C 17 2 19 0.102 0.546 View mutations
598 L 10 9 19 0.453 0.466 View mutations
599 L 15 4 19 0.240 0.536 View mutations
600 S 10 9 19 0.451 0.470 View mutations