P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
551 K 2 17 19 0.892 0.561 View mutations
552 F 0 19 19 0.987 0.597 View mutations
553 Q 5 14 19 0.683 0.445 View mutations
554 R 0 19 19 0.990 0.625 View mutations
555 E 6 13 19 0.679 0.577 View mutations
556 E 1 18 19 0.951 0.724 View mutations
557 R 0 19 19 1.000 0.774 View mutations
558 P 2 17 19 0.842 0.712 View mutations
559 L 18 1 19 0.069 0.296 View mutations
560 F 6 13 19 0.700 0.567 View mutations
561 P 18 1 19 0.081 0.400 View mutations
562 Q 1 18 19 0.966 0.607 View mutations
563 I 1 18 19 0.944 0.560 View mutations
564 L 0 19 19 0.997 0.601 View mutations
565 A 1 18 19 0.943 0.540 View mutations
566 T 13 6 19 0.384 0.479 View mutations
567 I 1 18 19 0.947 0.598 View mutations
568 E 2 17 19 0.912 0.563 View mutations
569 L 17 2 19 0.114 0.446 View mutations
570 L 17 2 19 0.080 0.383 View mutations
571 Q 11 8 19 0.426 0.491 View mutations
572 R 6 13 19 0.664 0.528 View mutations
573 S 2 17 19 0.886 0.551 View mutations
574 L 9 10 19 0.498 0.509 View mutations
575 P 0 19 19 0.983 0.702 View mutations