P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
526 Y 13 6 19 0.282 0.458 View mutations
527 L 19 0 19 0.000 0.362 View mutations
528 S 19 0 19 0.014 0.432 View mutations
529 P 9 10 19 0.452 0.510 View mutations
530 D 1 18 19 0.962 0.618 View mutations
531 L 5 14 19 0.761 0.549 View mutations
532 S 6 13 19 0.703 0.531 View mutations
533 K 1 18 19 0.949 0.544 View mutations
534 I 2 17 19 0.906 0.566 View mutations
535 S 6 13 19 0.683 0.441 View mutations
536 S 11 8 19 0.365 0.495 View mutations
537 N 16 3 19 0.146 0.435 View mutations
538 C 1 18 19 0.943 0.608 View mutations
539 P 0 19 19 0.993 0.662 View mutations
540 K 19 0 19 0.014 0.346 View mutations
541 A 12 7 19 0.410 0.463 View mutations
542 M 0 19 19 0.952 0.621 View mutations
543 R 14 5 19 0.268 0.441 View mutations
544 R 2 17 19 0.884 0.613 View mutations
545 L 7 12 19 0.614 0.517 View mutations
546 L 4 15 19 0.784 0.517 View mutations
547 S 18 1 19 0.042 0.407 View mutations
548 D 19 0 19 0.041 0.389 View mutations
549 C 7 12 19 0.666 0.520 View mutations
550 L 13 6 19 0.374 0.496 View mutations