P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 13 5 18 0.352 0.488 View mutations
2 S 10 9 19 0.453 0.441 View mutations
3 E 1 18 19 0.958 0.478 View mutations
4 T 14 5 19 0.292 0.465 View mutations
5 A 14 5 19 0.236 0.484 View mutations
6 P 18 1 19 0.076 0.537 View mutations
7 A 19 0 19 0.001 0.724 View mutations
8 A 19 0 19 0.006 0.722 View mutations
9 P 18 1 19 0.062 0.706 View mutations
10 A 19 0 19 0.019 0.785 View mutations
11 A 19 0 19 0.001 0.795 View mutations
12 P 15 4 19 0.197 0.660 View mutations
13 A 19 0 19 0.005 0.803 View mutations
14 P 17 2 19 0.100 0.756 View mutations
15 A 19 0 19 0.003 0.872 View mutations
16 E 19 0 19 0.001 0.868 View mutations
17 K 19 0 19 0.003 0.905 View mutations
18 T 18 1 19 0.055 0.838 View mutations
19 P 10 9 19 0.429 0.505 View mutations
20 V 19 0 19 0.016 0.891 View mutations
21 K 12 7 19 0.318 0.594 View mutations
22 K 19 0 19 0.010 0.916 View mutations
23 K 14 5 19 0.417 0.686 View mutations
24 A 15 4 19 0.299 0.713 View mutations
25 R 19 0 19 0.036 0.908 View mutations