P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 K 19 0 19 0.084 0.863 View mutations
27 S 19 0 19 0.006 0.875 View mutations
28 A 19 0 19 0.026 0.865 View mutations
29 G 19 0 19 0.006 0.824 View mutations
30 A 18 1 19 0.055 0.773 View mutations
31 A 19 0 19 0.003 0.788 View mutations
32 K 19 0 19 0.022 0.818 View mutations
33 R 9 10 19 0.525 0.453 View mutations
34 K 16 3 19 0.132 0.584 View mutations
35 A 10 9 19 0.449 0.460 View mutations
36 S 19 0 19 0.012 0.497 View mutations
37 G 14 5 19 0.355 0.488 View mutations
38 P 0 19 19 0.986 0.577 View mutations
39 P 5 14 19 0.682 0.443 View mutations
40 V 1 18 19 0.873 0.481 View mutations
41 S 1 18 19 0.879 0.471 View mutations
42 E 12 7 19 0.383 0.495 View mutations
43 L 19 0 19 0.023 0.438 View mutations
44 I 2 17 19 0.902 0.503 View mutations
45 T 4 15 19 0.801 0.467 View mutations
46 K 17 2 19 0.109 0.394 View mutations
47 A 4 15 19 0.772 0.542 View mutations
48 V 2 17 19 0.881 0.541 View mutations
49 A 8 11 19 0.528 0.507 View mutations
50 A 1 18 19 0.915 0.604 View mutations