P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 S 0 19 19 1.000 0.617 View mutations
52 K 0 19 19 0.988 0.613 View mutations
53 E 0 19 19 1.000 0.687 View mutations
54 R 2 17 19 0.862 0.558 View mutations
55 S 19 0 19 0.010 0.431 View mutations
56 G 2 17 19 0.886 0.666 View mutations
57 V 2 17 19 0.888 0.594 View mutations
58 S 14 5 19 0.323 0.402 View mutations
59 L 2 17 19 0.821 0.660 View mutations
60 A 1 18 19 0.909 0.701 View mutations
61 A 0 19 19 0.989 0.679 View mutations
62 L 0 19 19 1.000 0.683 View mutations
63 K 2 17 19 0.887 0.649 View mutations
64 K 5 14 19 0.811 0.607 View mutations
65 A 4 15 19 0.810 0.545 View mutations
66 L 0 19 19 0.982 0.753 View mutations
67 A 1 18 19 0.939 0.692 View mutations
68 A 1 18 19 0.949 0.735 View mutations
69 A 15 4 19 0.222 0.398 View mutations
70 G 3 16 19 0.813 0.783 View mutations
71 Y 0 19 19 0.999 0.918 View mutations
72 D 0 19 19 0.994 0.852 View mutations
73 V 0 19 19 1.000 0.917 View mutations
74 E 1 18 19 0.948 0.721 View mutations
75 K 1 18 19 0.959 0.681 View mutations