P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 N 0 19 19 1.000 0.761 View mutations
77 N 2 17 19 0.890 0.642 View mutations
78 S 0 19 19 1.000 0.681 View mutations
79 R 0 19 19 1.000 0.705 View mutations
80 I 1 18 19 0.949 0.676 View mutations
81 K 0 19 19 1.000 0.648 View mutations
82 L 0 19 19 0.981 0.619 View mutations
83 G 0 19 19 0.976 0.675 View mutations
84 L 9 10 19 0.529 0.512 View mutations
85 K 2 17 19 0.901 0.634 View mutations
86 S 18 1 19 0.103 0.410 View mutations
87 L 0 19 19 1.000 0.786 View mutations
88 V 0 19 19 1.000 0.863 View mutations
89 S 18 1 19 0.060 0.439 View mutations
90 K 17 2 19 0.160 0.379 View mutations
91 G 5 14 19 0.773 0.668 View mutations
92 T 19 0 19 0.000 0.248 View mutations
93 L 1 18 19 0.968 0.867 View mutations
94 V 11 8 19 0.428 0.455 View mutations
95 Q 0 19 19 1.000 0.832 View mutations
96 T 3 16 19 0.845 0.715 View mutations
97 K 9 10 19 0.580 0.517 View mutations
98 G 6 13 19 0.633 0.683 View mutations
99 T 3 16 19 0.785 0.718 View mutations
100 G 3 16 19 0.834 0.842 View mutations