P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 A 17 2 19 0.114 0.736 View mutations
152 K 14 5 19 0.255 0.638 View mutations
153 K 19 0 19 0.006 0.817 View mutations
154 T 18 1 19 0.049 0.735 View mutations
155 P 10 9 19 0.458 0.483 View mutations
156 K 19 0 19 0.002 0.722 View mutations
157 K 19 0 19 0.006 0.739 View mutations
158 A 18 1 19 0.085 0.656 View mutations
159 K 19 0 19 0.039 0.721 View mutations
160 K 18 1 19 0.165 0.694 View mutations
161 P 17 2 19 0.131 0.678 View mutations
162 A 19 0 19 0.054 0.809 View mutations
163 A 18 1 19 0.106 0.824 View mutations
164 A 19 0 19 0.041 0.885 View mutations
165 A 19 0 19 0.001 0.971 View mutations
166 G 19 0 19 0.009 0.987 View mutations
167 A 19 0 19 0.000 0.958 View mutations
168 K 19 0 19 0.002 0.990 View mutations
169 K 19 0 19 0.000 0.986 View mutations
170 A 19 0 19 0.000 0.948 View mutations
171 K 19 0 19 0.028 0.927 View mutations
172 S 19 0 19 0.031 0.913 View mutations
173 P 19 0 19 0.003 0.920 View mutations
174 K 19 0 19 0.002 0.921 View mutations
175 K 19 0 19 0.000 0.943 View mutations