P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 19 0 19 0.020 0.958 View mutations
127 K 18 1 19 0.156 0.924 View mutations
128 A 11 8 19 0.523 0.570 View mutations
129 K 19 0 19 0.042 0.965 View mutations
130 K 12 7 19 0.416 0.611 View mutations
131 P 14 5 19 0.289 0.705 View mutations
132 A 17 2 19 0.118 0.841 View mutations
133 G 19 0 19 0.010 0.905 View mutations
134 A 19 0 19 0.022 0.916 View mutations
135 A 19 0 19 0.000 0.922 View mutations
136 K 19 0 19 0.013 0.923 View mutations
137 K 16 3 19 0.140 0.796 View mutations
138 P 19 0 19 0.075 0.931 View mutations
139 K 18 1 19 0.061 0.928 View mutations
140 K 12 7 19 0.405 0.609 View mutations
141 A 19 0 19 0.005 0.943 View mutations
142 T 19 0 19 0.001 0.933 View mutations
143 G 19 0 19 0.001 0.930 View mutations
144 A 19 0 19 0.014 0.929 View mutations
145 A 19 0 19 0.001 0.894 View mutations
146 T 19 0 19 0.000 0.922 View mutations
147 P 13 6 19 0.303 0.646 View mutations
148 K 19 0 19 0.000 0.907 View mutations
149 K 19 0 19 0.007 0.899 View mutations
150 S 19 0 19 0.000 0.892 View mutations