P10412 (P10412)

Overview
Predicted structure (AF):
AF-P10412-F1-model_v4
Uniprot entry:
P10412
Gene:
P10412
Protein length:
219 residues
Mutations found:
4160
Benign based on D2Deep prediction:
2858 out of 4160 mutations
Pathogenic based on D2Deep prediction:
1302 out of 4160 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4160 mutations across 219 unique positions. There are 2858 benign and 1302 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 A 19 0 19 0.008 0.965 View mutations
177 K 19 0 19 0.031 0.935 View mutations
178 A 19 0 19 0.000 0.895 View mutations
179 A 19 0 19 0.001 0.920 View mutations
180 K 19 0 19 0.013 0.938 View mutations
181 P 19 0 19 0.001 0.852 View mutations
182 K 19 0 19 0.003 0.870 View mutations
183 K 19 0 19 0.001 0.883 View mutations
184 A 19 0 19 0.010 0.825 View mutations
185 P 19 0 19 0.002 0.859 View mutations
186 K 19 0 19 0.005 0.820 View mutations
187 S 18 1 19 0.050 0.766 View mutations
188 P 19 0 19 0.039 0.755 View mutations
189 A 16 3 19 0.176 0.716 View mutations
190 K 17 2 19 0.154 0.768 View mutations
191 A 19 0 19 0.049 0.813 View mutations
192 K 19 0 19 0.005 0.869 View mutations
193 A 19 0 19 0.013 0.835 View mutations
194 V 19 0 19 0.011 0.838 View mutations
195 K 19 0 19 0.060 0.886 View mutations
196 P 19 0 19 0.018 0.772 View mutations
197 K 19 0 19 0.008 0.857 View mutations
198 A 18 1 19 0.058 0.826 View mutations
199 A 18 1 19 0.038 0.845 View mutations
200 K 6 13 19 0.714 0.326 View mutations