P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 5 14 19 0.674 0.400 View mutations
227 G 15 4 19 0.242 0.493 View mutations
228 A 5 14 19 0.724 0.427 View mutations
229 C 0 19 19 1.000 0.415 View mutations
230 I 3 16 19 0.867 0.431 View mutations
231 T 3 16 19 0.835 0.437 View mutations
232 L 4 15 19 0.826 0.427 View mutations
233 G 0 19 19 1.000 0.466 View mutations
234 A 0 19 19 0.994 0.513 View mutations
235 Y 5 14 19 0.714 0.448 View mutations
236 L 6 13 19 0.662 0.443 View mutations
237 G 0 19 19 0.998 0.490 View mutations
238 H 0 19 19 0.997 0.481 View mutations
239 K 0 19 19 0.976 0.475 View mutations