P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 L 19 0 19 0.018 0.584 View mutations
202 Y 16 3 19 0.149 0.561 View mutations
203 G 19 0 19 0.000 0.614 View mutations
204 P 19 0 19 0.000 0.656 View mutations
205 S 19 0 19 0.004 0.659 View mutations
206 M 19 0 19 0.038 0.651 View mutations
207 R 19 0 19 0.026 0.581 View mutations
208 P 19 0 19 0.007 0.604 View mutations
209 L 19 0 19 0.002 0.658 View mutations
210 F 19 0 19 0.001 0.613 View mutations
211 D 18 1 19 0.053 0.603 View mutations
212 F 11 8 19 0.381 0.498 View mutations
213 S 15 4 19 0.196 0.588 View mutations
214 W 19 0 19 0.090 0.657 View mutations
215 L 17 2 19 0.123 0.615 View mutations
216 S 13 6 19 0.294 0.531 View mutations
217 L 19 0 19 0.015 0.659 View mutations
218 K 12 7 19 0.429 0.482 View mutations
219 T 17 2 19 0.154 0.569 View mutations
220 L 17 2 19 0.183 0.600 View mutations
221 L 19 0 19 0.024 0.645 View mutations
222 S 18 1 19 0.049 0.591 View mutations
223 L 17 2 19 0.161 0.559 View mutations
224 A 14 5 19 0.254 0.525 View mutations
225 L 8 11 19 0.576 0.431 View mutations