P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 P 0 19 19 0.997 0.689 View mutations
202 T 9 10 19 0.483 0.505 View mutations
203 R 13 6 19 0.319 0.449 View mutations
204 K 13 6 19 0.288 0.445 View mutations
205 H 11 8 19 0.467 0.476 View mutations
206 Y 6 13 19 0.675 0.562 View mutations
207 Q 1 18 19 0.909 0.594 View mutations
208 P 0 19 19 0.971 0.817 View mutations
209 Y 2 17 19 0.856 0.535 View mutations
210 A 19 0 19 0.084 0.111 View mutations
211 P 4 15 19 0.776 0.700 View mutations
212 P 3 16 19 0.814 0.707 View mutations
213 R 0 19 19 0.999 0.801 View mutations
214 D 0 19 19 0.940 0.928 View mutations
215 F 0 19 19 0.998 0.804 View mutations
216 A 0 19 19 0.926 0.811 View mutations
217 A 7 12 19 0.644 0.622 View mutations
218 Y 4 15 19 0.775 0.694 View mutations
219 R 14 5 19 0.286 0.341 View mutations
220 S 19 0 19 0.068 0.271 View mutations