P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 18 1 19 0.055 0.772 View mutations
152 P 12 7 19 0.374 0.541 View mutations
153 F 19 0 19 0.033 0.786 View mutations
154 W 19 0 19 0.023 0.695 View mutations
155 V 19 0 19 0.032 0.786 View mutations
156 L 16 3 19 0.173 0.736 View mutations
157 V 19 0 19 0.002 0.837 View mutations
158 V 18 1 19 0.163 0.711 View mutations
159 V 13 6 19 0.262 0.586 View mutations
160 G 19 0 19 0.039 0.875 View mutations
161 G 19 0 19 0.011 0.678 View mutations
162 V 8 11 19 0.546 0.431 View mutations
163 L 3 16 19 0.763 0.342 View mutations
164 A 11 8 19 0.424 0.501 View mutations
165 C 19 0 19 0.002 0.566 View mutations
166 Y 6 13 19 0.650 0.423 View mutations
167 S 17 2 19 0.116 0.498 View mutations
168 L 11 8 19 0.338 0.476 View mutations
169 L 17 2 19 0.114 0.532 View mutations
170 V 18 1 19 0.069 0.493 View mutations
171 T 8 11 19 0.554 0.433 View mutations
172 V 17 2 19 0.139 0.578 View mutations
173 A 18 1 19 0.059 0.566 View mutations
174 F 18 1 19 0.037 0.534 View mutations
175 I 19 0 19 0.049 0.623 View mutations