P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.000 0.704 View mutations
2 L 18 1 19 0.116 0.790 View mutations
3 R 4 15 19 0.775 0.258 View mutations
4 L 19 0 19 0.006 0.831 View mutations
5 L 19 0 19 0.004 0.902 View mutations
6 L 19 0 19 0.028 0.867 View mutations
7 A 19 0 19 0.001 0.846 View mutations
8 L 19 0 19 0.012 0.880 View mutations
9 N 19 0 19 0.010 0.996 View mutations
10 L 16 3 19 0.162 0.762 View mutations
11 F 19 0 19 0.002 0.930 View mutations
12 P 16 3 19 0.177 0.766 View mutations
13 S 19 0 19 0.001 0.978 View mutations
14 I 19 0 19 0.000 0.959 View mutations
15 Q 19 0 19 0.001 0.865 View mutations
16 V 19 0 19 0.006 0.902 View mutations
17 T 19 0 19 0.015 0.953 View mutations
18 G 15 4 19 0.227 0.536 View mutations
19 N 16 3 19 0.180 0.578 View mutations
20 K 19 0 19 0.043 0.443 View mutations
21 I 12 7 19 0.443 0.414 View mutations
22 L 18 1 19 0.053 0.401 View mutations
23 V 0 19 19 0.985 0.561 View mutations
24 K 16 3 19 0.165 0.515 View mutations
25 Q 0 19 19 0.998 0.536 View mutations