P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 I 18 1 19 0.078 0.682 View mutations
177 F 16 3 19 0.224 0.542 View mutations
178 W 19 0 19 0.013 0.519 View mutations
179 V 15 4 19 0.180 0.567 View mutations
180 R 18 1 19 0.107 0.531 View mutations
181 S 19 0 19 0.000 0.429 View mutations
182 K 19 0 19 0.001 0.465 View mutations
183 R 19 0 19 0.005 0.467 View mutations
184 S 18 1 19 0.120 0.442 View mutations
185 R 17 2 19 0.073 0.374 View mutations
186 L 19 0 19 0.001 0.453 View mutations
187 L 13 6 19 0.327 0.436 View mutations
188 H 17 2 19 0.167 0.383 View mutations
189 S 0 19 19 0.933 0.828 View mutations
190 D 3 16 19 0.738 0.775 View mutations
191 Y 0 19 19 1.000 0.910 View mutations
192 M 4 15 19 0.705 0.747 View mutations
193 N 1 18 19 0.926 0.899 View mutations
194 M 1 18 19 0.867 0.947 View mutations
195 T 5 14 19 0.715 0.652 View mutations
196 P 8 11 19 0.559 0.565 View mutations
197 R 10 9 19 0.431 0.487 View mutations
198 R 5 14 19 0.715 0.575 View mutations
199 P 5 14 19 0.644 0.575 View mutations
200 G 0 19 19 0.987 0.810 View mutations