P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 S 14 5 19 0.286 0.409 View mutations
277 D 19 0 19 0.039 0.460 View mutations
278 R 19 0 19 0.022 0.289 View mutations
279 P 7 12 19 0.637 0.516 View mutations
280 T 10 9 19 0.456 0.499 View mutations
281 F 3 16 19 0.851 0.472 View mutations
282 E 13 6 19 0.341 0.431 View mutations
283 E 15 4 19 0.253 0.409 View mutations
284 I 0 19 19 0.999 0.516 View mutations
285 Q 13 6 19 0.401 0.438 View mutations
286 N 19 0 19 0.000 0.547 View mutations
287 H 18 1 19 0.141 0.363 View mutations
288 P 3 16 19 0.791 0.512 View mutations
289 W 17 2 19 0.163 0.385 View mutations
290 M 12 7 19 0.347 0.485 View mutations
291 Q 18 1 19 0.091 0.705 View mutations
292 D 16 3 19 0.132 0.661 View mutations
293 V 19 0 19 0.001 0.802 View mutations
294 L 19 0 19 0.003 0.784 View mutations
295 L 19 0 19 0.000 0.772 View mutations
296 P 19 0 19 0.000 0.807 View mutations
297 Q 18 1 19 0.058 0.815 View mutations
298 E 19 0 19 0.011 0.789 View mutations
299 T 19 0 19 0.010 0.807 View mutations
300 A 19 0 19 0.003 0.772 View mutations