P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 W 0 19 19 1.000 0.854 View mutations
227 S 12 7 19 0.325 0.368 View mutations
228 L 0 19 19 1.000 0.961 View mutations
229 G 0 19 19 1.000 0.976 View mutations
230 I 1 18 19 0.947 0.804 View mutations
231 L 0 19 19 0.998 0.912 View mutations
232 L 0 19 19 1.000 0.807 View mutations
233 Y 1 18 19 0.972 0.761 View mutations
234 D 0 19 19 1.000 0.716 View mutations
235 M 5 14 19 0.729 0.679 View mutations
236 V 17 2 19 0.095 0.223 View mutations
237 C 0 19 19 0.989 0.723 View mutations
238 G 0 19 19 1.000 0.932 View mutations
239 D 0 19 19 0.999 0.694 View mutations
240 I 1 18 19 0.908 0.716 View mutations
241 P 14 5 19 0.357 0.321 View mutations
242 F 13 6 19 0.442 0.393 View mutations
243 E 4 15 19 0.757 0.557 View mutations
244 H 19 0 19 0.002 0.402 View mutations
245 D 5 14 19 0.728 0.564 View mutations
246 E 7 12 19 0.577 0.441 View mutations
247 E 19 0 19 0.010 0.414 View mutations
248 I 0 19 19 0.999 0.651 View mutations
249 I 5 14 19 0.740 0.513 View mutations
250 R 16 3 19 0.203 0.504 View mutations