P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 G 11 8 19 0.443 0.492 View mutations
252 Q 19 0 19 0.016 0.486 View mutations
253 V 6 13 19 0.690 0.451 View mutations
254 F 19 0 19 0.029 0.529 View mutations
255 F 2 17 19 0.902 0.535 View mutations
256 R 12 7 19 0.463 0.443 View mutations
257 Q 16 3 19 0.220 0.486 View mutations
258 R 19 0 19 0.018 0.504 View mutations
259 V 19 0 19 0.017 0.402 View mutations
260 S 19 0 19 0.000 0.412 View mutations
261 S 18 1 19 0.092 0.484 View mutations
262 E 6 13 19 0.734 0.502 View mutations
263 C 17 2 19 0.128 0.427 View mutations
264 Q 15 4 19 0.250 0.410 View mutations
265 H 19 0 19 0.044 0.541 View mutations
266 L 19 0 19 0.018 0.391 View mutations
267 I 1 18 19 0.948 0.705 View mutations
268 R 19 0 19 0.070 0.392 View mutations
269 W 13 6 19 0.298 0.460 View mutations
270 C 0 19 19 1.000 0.601 View mutations
271 L 0 19 19 1.000 0.780 View mutations
272 A 19 0 19 0.002 0.376 View mutations
273 L 19 0 19 0.011 0.359 View mutations
274 R 9 10 19 0.510 0.438 View mutations
275 P 19 0 19 0.000 0.323 View mutations