P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 15 4 19 0.295 0.543 View mutations
77 W 6 13 19 0.612 0.419 View mutations
78 G 11 8 19 0.487 0.484 View mutations
79 E 15 4 19 0.275 0.560 View mutations
80 L 11 8 19 0.497 0.476 View mutations
81 P 15 4 19 0.198 0.552 View mutations
82 N 7 12 19 0.669 0.415 View mutations
83 G 2 17 19 0.823 0.393 View mutations
84 T 18 1 19 0.093 0.602 View mutations
85 R 18 1 19 0.092 0.546 View mutations
86 V 13 6 19 0.275 0.498 View mutations
87 P 1 18 19 0.935 0.520 View mutations
88 M 11 8 19 0.432 0.493 View mutations
89 E 11 8 19 0.411 0.490 View mutations
90 V 19 0 19 0.014 0.354 View mutations
91 V 19 0 19 0.002 0.414 View mutations
92 L 19 0 19 0.002 0.414 View mutations
93 L 10 9 19 0.445 0.424 View mutations
94 K 19 0 19 0.000 0.508 View mutations
95 K 17 2 19 0.108 0.405 View mutations
96 V 4 15 19 0.791 0.466 View mutations
97 S 19 0 19 0.032 0.457 View mutations
98 S 19 0 19 0.050 0.546 View mutations
99 G 6 13 19 0.662 0.422 View mutations
100 F 5 14 19 0.749 0.377 View mutations